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Causes and Risk Factors

Barrett's esophagus develops as a result of abnormal changes (called metaplasia) in the lining of the esophagus. The exact cause for Barrett's esophagus is unknown; however, the condition is thought to be related to chronic acid reflux (also called heartburn or indigestion).

Acid reflux occurs when stomach acid and juices (i.e., enzymes that aid in digestion) back up (reflux) into the esophagus. Over time, severe acid reflux can cause gastroesophageal reflux diseas...Read the full article