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Causes and Risk Factors

Post a new topicby contentuser on Sun Mar 09, 2008 2:37 pm


Causes and Risk Factors

Hemochromatosis is characterized by a build-up of iron in cells of the body that causes tissue damage and can lead to organ failure. Primary hemochromatosis results from a genetic (inherited) abnormality of the HFE gene, which helps regulate iron absorption.

More than 20 different mutations of this gene have been identified and the two most common have been labeled C282Y and H63D. Juvenile hemochromatosis and neonatal hemochromatosis are caused by a mutation of an...Read the full article

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